Solution Overview & Team Lead Details

Our Organization

Rhea's Factory

What is the name of your solution?

Rhea's Factory

Provide a one-line summary of your solution.

We design and develop novel enzymes for scalable biocatalysis processes to degrade plastic (biorecycling).

In what city, town, or region is your solution team headquartered?

Berkeley, CA, USA

In what country is your solution team headquartered?

  • United States

What type of organization is your solution team?

For-profit, including B-Corp or similar models

Film your elevator pitch.

What specific problem are you solving?

Did you know that plastics are now a permanent marker of our geological era, embedding themselves into the Earth's fossil record? Despite their industrial benefits, the durability of plastics has led to their persistence in nature for centuries. Since their introduction in the 1950s, approximately 9.5 billion tons of plastic have been produced, with about 75% still present on our planet. The overwhelming production and underwhelming recycling of plastics left the majority of the plastics to accumulate in landfills, incinerators, or worse, in our natural environment and oceans. Currently, we lack a large-scale solution to effectively remove this accumulating waste and put them back into the circular economy.

Plastics are crucial in our daily lives, but the imbalance between their high production rate and inadequate end-of-life management results in lost energy, economic challenges, and significant carbon emissions. The main hurdle to increasing plastic recycling rates is the difficulty in processing mixed plastics, which are often left unrecycled due to their complex chemistry and composition. Traditional recycling methods, which primarily involve thermal processing, require extensive sorting and are ineffective for many types of plastics, such as films or mixed materials. This diversity poses a significant challenge for recyclers and manufacturers seeking efficient and sustainable recycling methods.

Plastic produced since 1950s

9.5 B tons

Discarded plastic never been recycled

6 B tons

Dumped in a landfill or incinerated

>90%

Leaking into our oceans

12 M tons/y

Discarded as plastic waste

$100 B/y

Customers, like plastic manufacturers face significant pressure due to government mandates and consumer demands for recycled content in their products. Yet, the existing recycling ecosystem fails to provide high-quality materials that meet both manufacturers' requirements and regulatory standards. This inadequacy forces a reliance on virgin materials, highlighting the critical need for innovation in recycling technologies and a shift towards a circular plastics economy. There is an urgent need for circular plastics economy and we lack innovation in plastic recycling technologies.

What is your solution?

Rhea’s Factory designs novel enzyme blends and develops scalable biocatalysis processes utilizing the power of ML algorithms. Our innovative enzyme blends break down even the most complex, unrecyclable plastics back into their original, high-quality building blocks. These building blocks are indistinguishable from those derived from fossil fuels, enabling the production of premium plastics infinitely that meet both regulatory requirements and manufacturers' high standards, addressing our customers’ critical pain points. This means manufacturers can finally tap into the full potential of recycled plastics, achieving high recycling rates without sacrificing material quality. Our innovation not only diverts waste from landfills but also taps into the economic potential of previously unusable plastic waste, supporting the transition to a circular plastics bioeconomy demanded by governments and consumers alike.

Who does your solution serve, and in what ways will the solution impact their lives?

Enzymatic plastic recycling is considered one of the best sustainable methods for several reasons.

  1. First, it's highly efficient. Enzymes can specifically target and break down plastics like PET, often found in bottles, into their original building blocks. This process allows for recycling at a molecular level, making it more thorough than traditional mechanical recycling.
  2. Second, it's environmentally friendly. Enzymatic recycling usually operates under mild conditions, requiring less energy and producing fewer greenhouse gases compared to conventional methods. Plus, the process doesn't generate harmful byproducts.
  3. Third, it supports the creation of high-quality recycled materials. Unlike mechanical recycling, which can degrade the quality of plastics over time, enzymatic recycling can maintain or even improve the quality of the recycled material. This high quality enables the recycled materials to be used in more applications.
  4. Lastly, enzymatic recycling helps in dealing with plastic waste more effectively. Traditional methods can't recycle certain types of plastics, but enzymatic processes have the potential to handle a wider range of plastic materials. This versatility is key in addressing the global plastic waste challenge.

How are you and your team well-positioned to deliver this solution?

Our team, currently consists of two full time co-founders, is drawing upon a rich experience and expertise in both the scientific and technological domains. 

Arzu Sandıkçı, PhD

Arzu, our co-founder and CEO, has a rich background in molecular biology and biochemistry, where her expertise in enzyme mechanisms and molecular interactions has been refined through years of scholarly research. Transitioning to the fast-paced world of biotech, she has broadened her expertise to include the discovery and engineering of enzymes and bacterial genomes. Her focus is on enhancing their practicality for real-world applications, particularly in synthetic biology and pharmaceuticals.

Arzu is known for her initiative and compassionate approach to leadership, with a vibrant passion for leveraging her scientific knowledge to make a lasting, positive mark on the environment.

With nearly two decades of experience as a biochemist and enzyme engineer, her journey has been characterized by a deep dive into the complexities of enzyme engineering and synthetic biology within both academic circles and the biotech industry. Arzu's most recent endeavor saw her at the core of a climate-tech startup, where she was not just the first team member but also led the bioengineering department. There, she was key in shaping the technology strategy and establishing the foundational technical framework of the company, driven by her dedication to making a meaningful contribution to the health of our planet.

Mert Topçu, MBA

Mert, our co-founder and CTO, perfectly complements Arzu's expertise in science with his extensive background in the high-tech sector. With a career spanning over twenty years at leading firms like Google and Amazon, Mert has played a significant role in creating and launching groundbreaking products, utilizing the latest in machine learning, including developments in natural language processing. His deep passion for technology and constant exploration of new advancements have made him a key asset to our team.

As an expert in technology development and management, Mert's experience is vast, having contributed to major projects at Google, Amazon, and Western Digital. His work has been pivotal in the success of products such as Google's Smart Speakers and Smart Displays, as well as YouTube's Trust and Safety algorithms.

Mert's innovation extends beyond technology; he's also an accomplished athlete. As a dedicated age group triathlete, he has completed several full and half Ironman distances, even securing a win in his age group at the 2023 Santa Cruz Olympic Distance Triathlon. His diverse skills and achievements highlight his innovative spirit in machine learning, health and fitness technology, and strategic product management, making him an invaluable member of our leadership team.

Together, Arzu and Mert have a powerful synergy of scientific insight and technological innovation. Their combined decades of experience are underpinned by a shared commitment to leveraging their expertise for meaningful impact. This alignment in values and vision—to drive technological and scientific advancements for a better future—makes our team not just unique, but exceptionally qualified to lead our startup towards its ambitious goals.

Which dimension of the Challenge does your solution most closely address?

Other

Which of the UN Sustainable Development Goals does your solution address?

  • 12. Responsible Consumption and Production
  • 13. Climate Action
  • 15. Life on Land

What is your solution’s stage of development?

Prototype

Please share details about why you selected the stage above.

As of early March 2024, Rhea's Factory is advancing through the prototyping stage of our groundbreaking technology. Our focus is on an enzyme blend designed to tackle what was once considered unrecyclable: complex, multi-layered packaging materials, converting them back into their fundamental components. Initial tests have validated the efficacy of our enzymes on single-type post-consumer plastics. Currently, our efforts are concentrated on proving the capability of this enzyme blend to process intricate, layered materials. Specifically, our prototype aims to demonstrate the effective breakdown of poly-coated paper using a duo of enzymes, including a superior plastic-degrading enzyme sourced under license from the University of Texas at Austin.

In conjunction with our work on enzyme blend prototyping, we are diligently developing the foundation of our REDAI (Rhea's Enzyme Development Artificial Intelligence) architecture. This effort is illustrated by our creation of approximately 100 sequence variations derived from the enzyme targeted for enhancement. These variations serve as a basis for evaluating initial fitness, functionality, and thermostability, providing crucial data to refine and advance our enzyme design process.

Why are you applying to Solve?

The path we are on is long and difficult however has significant potential impact on sustainability and climate hence we need support from community of social impact leaders. As well as, our technology can be categorized as hard tech which means we need the proper financial support during the development and adaption of the technology phases.

In which of the following areas do you most need partners or support?

  • Business Model (e.g. product-market fit, strategy & development)
  • Technology (e.g. software or hardware, web development/design)

Who is the Team Lead for your solution?

Arzu Sandikci

More About Your Solution

What makes your solution innovative?

Rhea’s Factory has a threefold differentiation approach in the competitive landscape:

1.     Stable and compatible enzyme blends instead of single enzyme: Mixed and layered materials, like packaging, are degraded to their original building blocks by Rhea’s highly stable, re-usable enzyme blends, all in one-pot. This also lifts the burden from pretreatment process requirements and reduce the cost of the overall recycling process.

2.     Eco friendly solvent-based bio catalysis: Our innovative approach involves developing plastic-degrading enzyme blends tailored to their environmental context, utilizing unconventional and greener solvents.

3.     Machine learning algorithms (Protein Language Model) accelerated Design-Build-Test-Learn cycle specifically optimized for enzymes degrading different chemistries of plastics.

Describe in simple terms how and why you expect your solution to have an impact on the problem.

At Rhea's Factory, we are setting a new standard in plastic recycling with our proprietary enzyme blends. Our innovative REBs are specifically designed to break down a diverse array of plastics efficiently, functioning seamlessly together in a single process. By leveraging advanced machine learning models, we provide comprehensive insights into enzyme development, significantly accelerating R&D while reducing costs. Our approach ensures scalability and adaptability in addressing the challenges of plastic waste.

STABLE & COMPATIBLE ENZYME BLENDS

Our unique enzyme blends are engineered to tackle mixed and layered materials, converting them back into their original building blocks within a single, efficient process. This synergy among our enzymes enables the successful recycling of materials previously deemed non-recyclable, streamlining the biorecycling process and making it more cost-effective. Our commitment to stability and compatibility underlines our dedication to innovative and sustainable recycling solutions.

OPTIMIZED for SUBSTRATE SELECTIVITY

Rhea’s enzymes are adept at targeting and breaking down crystalline polymers, a common challenge in recycling complex mixed materials. This substrate selectivity allows for the effective recycling of challenging materials under milder, eco-friendlier conditions, showcasing our dedication to environmental sustainability and efficiency.

What are your impact goals for your solution and how are you measuring your progress towards them?

Ensure sustainable consumption and production patterns

Rhea’s Factory is pioneering the future of plastic recycling through its innovative enzymatic recycling approach, a process that transforms plastics back into their original, high-quality raw materials. By addressing the critical global challenge of plastic waste, which has plagued our environment and oceans due to the durable nature of plastics and inadequate recycling technologies, Rhea’s Factory offers a sustainable and efficient solution. Our unique proposition lies in developing novel enzyme blends and scalable biocatalysis processes powered by machine learning algorithms, designed to break down even the most complex, unrecyclable plastics. This technological advancement enables the production of premium plastics from recycled materials, meeting the highest standards of quality and sustainability required by manufacturers and regulators alike.

Describe the core technology that powers your solution.

The integration of AI-powered technologies, particularly large language models into the enzyme development process signifies a remarkable shift in the industry. Just as these models have revolutionized various sectors, their application in protein engineering holds immense promise. The fusion of cutting-edge machine learning with the digitization and modeling of biological systems is paving the way for a future where the entire process of protein and enzyme engineering, from design to application, will be revolutionized by artificial intelligence systems. This vision not only aligns with the latest advancements in technology but also promises to reshape the biotechnology landscape, positioning our startup at the forefront of innovation in enzymatic recycling and protein engineering.

Which of the following categories best describes your solution?

A new application of an existing technology

Please select the technologies currently used in your solution:

  • Artificial Intelligence / Machine Learning
  • Biotechnology / Bioengineering

In which countries do you currently operate?

  • United States
Your Team

How many people work on your solution team?

Two co-founders of Rhea's Factory, Arzu and Mert are working full time and will continue to do so.

How long have you been working on your solution?

About 6 months.

Tell us about how you ensure that your team is diverse, minimizes barriers to opportunity for staff, and provides a welcoming and inclusive environment for all team members.

We are a very small startup focusing on building the technology right now.

Your Business Model & Funding

What is your business model?

During enzyme development phase of our company, our primary revenue focus is on bulk enzyme sales, with licensing our enzymes and technology as a potential complementary secondary path.


Do you primarily provide products or services directly to individuals, to other organizations, or to the government?

Organizations (B2B)

What is your plan for becoming financially sustainable, and what evidence can you provide that this plan has been successful so far?

Rhea's Factory aims to consistently generate high margins by employing several key strategies in the face of competition, both today and in the future:

·      Unique Blend-Based Approach: Rhea's focus on blend-based enzymatic solutions sets us apart from competitors. While others may focus on single-enzyme solutions, our holistic approach optimizes the recycling processes especially for layered or mixed plastic waste.

·      IP and Proprietary Enzymes: Our development of proprietary enzymes will give us a significant edge. These unique enzymes will offer protection and a competitive advantage, allowing us to control our costs while providing tailored solutions to our customers.

·      Diversified Market Opportunities: By targeting large industrial sectors such as packaging and automotive, Rhea's Factory can tap into diverse revenue streams, reducing risk and ensuring consistent cash flow. This diversified approach insulates us from market fluctuations. Partner w/ Brands: The growing global emphasis on sustainability and environmentally responsible practices creates a positive environment for Rhea's Factory. Brands are increasingly seeking eco-friendly solutions, allowing us to command premium pricing for our products through key partnerships with brands in multiple different sectors.

Solution Team

 
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