AMRSense: Empowering Communities with a Proactive OneHealth Ecosystem

Please select all the technologies currently used in your solution:

• Artificial Intelligence / Machine Learning
• Behavioral Technology
• Big Data
• Crowd Sourced Service / Social Networks
• Software and Mobile Applications

What “public good” does your solution provide?

1. Community-Centric Social Network Model: a replicable model for identifying and engaging focal points for awareness for public health initiatives, open for adaptationion in other public health initiatives.
2. Open-Sourced Data Ecosystem: modular, federated data ecosystem using APIs that will be globally accessible and can be adapted and used by other countries. 
3. Integrative modeling framework. Open-sourced modeling platform similar to this platform (IFHP) was created by PI's lab. Exploration of non-personal open-data and community-contributed models will be encouraged through a datahub and modelzoo.
4. AMRaura Scorecard: a tool for policymakers, healthcare providers, and researchers useful for integrative modeling, monitoring trends, guiding interventions, and resource allocation. 
5. AMR Awareness, Education Resources, AMR Playbook: a suite of awareness and education materials to enhance understanding and promote responsible antibiotic use among healthcare providers, the general public, to guidelines and best practices for AMR management.
6. Knowledge Communities and Campaigns: campaigns, workshops, health talks, and training modules, enhancing AMR awareness.
7. Research and Knowledge Sharing: publish findings in peer-reviewed publications,  white papers 

By providing these public goods, AMRSense aims to improve global health security, support evidence-based decision-making, and foster a collaborative approach to addressing the critical challenge of antimicrobial resistance.

How will your solution create tangible impact, and for whom?

We aim to create a tangible impact through a cohesive series of activities, outputs, and outcomes:

1. Empowering community health workers (CHWs) with AI-assisted tools and a federated data ecosystem for efficient AMR data collection.

   • Output: Improved quality and reliability of AMR surveillance data.
   • Outcome: Enhanced capacity for healthcare providers and policymakers to monitor AMR trends and implement targeted interventions.

2. Conducting education campaigns and training modules to raise awareness about responsible antibiotic use among healthcare providers and the public.

   • Output: Increased awareness and understanding of AMR.
   • Outcome: Reduced misuse of antibiotics, contributing to a decrease in the spread of AMR.

3. Implementing the AMRaura scorecard to integrate diverse datasets and provide insights into AMR dynamics.

   • Output: A tool for monitoring AMR trends and guiding interventions.
   • Outcome: Informed decision-making leading to more effective AMR management strategies.

4. Utilizing advanced analytics to process integrated data for identifying AMR trends and predicting resistance hotspots.

   • Output: Actionable insights for AMR management.
   • Outcome: Data-driven policy formulation and resource allocation for AMR containment.

AMRsense is supported by our background work, evidence on strengthening systems with data, and the success of initiatives such as ICMR IAMRSN and mMitra. 

How will you scale your impact over the next year and the next 3 years?

Over the next one year, AMRSense aims to scale its impact by:

1. Expansion and integration into the District-hospital based surveillance in 700+ district hospitals under an MoU between ICMR, AIIMS, and NHSRC. 

2. Develop plugins for social initiatives of corporate partnerships such as Tata 1mg.com

3. Strengthening National Partnerships: Leveraging our lead-role in the Delhi Science and Technology Cluster (DRIIV), we will liaise with government agencies, non-governmental organizations, and private sector partners to leverage their networks and resources for wider deployment.

In the next three years, the goal is to:

1. Policy Integration: Work closely with policymakers to integrate AMRSense's data-driven insights into national AMR surveillance and management strategies.
2. Technology Enhancement: Through inter-cluster collaboration currently existing with Bangalore and Pune clusters, and with organizations leading AMR diagnostics such as CCAMP, we plan to onboard new technology innovations into AMRSense's open-source ecosystem

3. Global Outreach: The presence of PATH in nearby LMICs such as Bangladesh will be instrumental in creating a global outreach for AMRSense. We will explore opportunities to adapt and implement AMRSense in other countries facing similar AMR challenges, particularly in the South East Asia region, leveraging India's experience as a model.

How are you measuring success against your impact goals?

A Knowledge, Action, and Practice approach will be used to assess the success of the solution. Baseline data for the following specific and measurable indicators will be tracked over time to measure success against impact goals

1. Community Engagement: We will assess the level of community engagement and participation of healthcare workers (HCWs) and frontline workers (FLWs) in AMR surveillance and awareness efforts. The increase in the number actively using AMRSense and participating in awareness activities will be recorded.

2. Quality and Quantity of Data Collected: Number of District hospitals onboarded; overall volume, completeness, and accuracy of data collected by HCWs, FLWs, and laboratories using AMRSense. Randomly selected subsets will be evaluated for the accuracy of the recorded antibiotic prescriptions and AMR cases.

3. Usage of AMRaura Scorecard: adoption and utilization of the AMRaura scorecard by IAMRSN sites, district hospitals, and district health officials.  We will record the number of policy consults arising from the use of the AMRaura scorecard.

4. Awareness and Behavior Change: We will assess the effectiveness of education campaigns and training modules in raising awareness and promoting responsible antibiotic use. A reduction in inappropriate antibiotic prescriptions, measured through pre- and post-campaign surveys will indicate behavior change.

In which countries do you currently operate?

• Bangladesh
• Bhutan
• India
• Nepal
• Myanmar

In which countries do you plan to deploy your solution within the next 3 years?

• India

What barriers currently exist for you to accomplish your goals in the next year and the next 3 years? How do you plan to overcome these barriers?

1. Financial Constraints: Effective engagement with health care workers(HCWs) and frontline workers(FLWs) requires significant financial resources. Additionally, our social badges proposed to motivate communities through health services add further costs. To build and sustain the momentum during the execution, we will roll out AMRSense in three phases: 

   1. Ignite: Stakeholder engagements, gap understanding, community education, human-centered design iteration.

   2. Overdrive: pilot AMRSense at the block level and building of social recognition and rewards. 

   3. Autopilot: Identification of community and lab champions for targeted interventions such as awareness campaigns and data pioneers.

2. Technical Challenges: 
   1. Privacy. AMRSense will not store individual data on our servers. Federated aggregated data to assess the AMR "aura" at the block level instead.
   2. Interoperability: a common data model and WHONet-compliant APIs for data capture. 
3. Cultural and Educational barriers: resistance to technology adoption will managed by early engagement with HCWs and FLWs, human-centered design, and iterative development.

4. Policy and Regulatory Hurdles: Collaboration with ICMR on the team will help understand and navigate the globally shifting landscape of AI and patient privacy. 

5. Market Challenges: Establishing the value proposition of AMRSense through pilot projects, dashboards, AMR Scorecards, and integration with pharmacy solutions will build credibility.

http://tavlab.iiitd.edu.in/amr_website/

If you have additional video content that explains your solution, provide a YouTube or Vimeo link or upload a video here.

What type of organization is your solution team?

Why are you applying to The Trinity Challenge?

The Trinity Challenge aligns perfectly with our prior collective work and mission to combat antimicrobial resistance at the ground level in LMICs. AMRSense empowers data collection and leverages AI and analytics to improve AMR surveillance at scale, which aligns perfectly with The Trinity Challenge's objectives. In general, AMRSense resonates with the Challenge's focus on harnessing the power of data to tackle AMR and health emergencies.

Barriers The Trinity Challenge Can Help Overcome:

1. Financial Constraints: Adoption of digital solutions requires an initial phase of value-building exercise with frontline workers. The Challenge provides a unique opportunity to overcome this financial hurdle and enable a self-driven data ecosystem extending beyond the pilot regions proposed.
2. Technical Challenges: Access to The Trinity Challenge's network of experts and resources can help us refine our strategy, ensuring the robustness and scalability of our solution.
3. Policy and Regulatory Hurdles: The Challenge can facilitate connections with policymakers and regulatory bodies, aiding us in navigating legal frameworks and advocating for policies that support AMR surveillance and management.
4. Market Challenges: The visibility and credibility gained through The Trinity Challenge can help us establish the value proposition of AMRSense, attracting additional partners and stakeholders for wider adoption.

What organization(s) would you like to collaborate with to initiate, accelerate, or scale your solution?

1. The World Health Organization (WHO):

   • Value Proposition: Provides global leadership in AMR surveillance and policy guidance.
   • How It Helps: Access to global AMR guidelines and networks, enabling AMRSense to align with international standards and expand its impact.

2. The Centers for Disease Control and Prevention (CDC):

   • Value Proposition: Expertise in infectious disease surveillance and response.
   • How It Helps: integration and refinement of AMRSense surveillance tools and methodologies.

3. ReAct – Action on Antibiotic Resistance:

   • Value Proposition: Advocacy and policy development focused on AMR.
   • How It Helps: Assists in raising awareness about AMRSense and advocating for policies that support its adoption and scaling.

4. Global Antibiotic Research and Development Partnership (GARDP):

   • Value Proposition: Research and development of new antibiotics.
   • How It Helps: Provides insights into emerging antibiotic treatments and resistance patterns, enriching AMRSense's data ecosystem.

5. Fleming Fund:

   • Value Proposition: Financial support for AMR surveillance capacity-building in LMICs.
   • How It Helps: Offers funding opportunities to expand AMRSense's implementation in LMICs, enhancing its reach and impact.

6. Médecins Sans Frontières (MSF):

   • Value Proposition: Medical programs addressing AMR in LMICs.
   • How It Helps: Shares practical insights and experiences from AMR management in resource-limited settings, informing AMRSense's effective approach to address AMR challenges.